EurekAlert!

Understanding biology in space: platforms, tools, and databases for spatial transcriptomics

The rapid development of spatial transcriptomics (ST) technologies has greatly advanced the understanding of gene expression, tissue architecture, cellular composition, and disease mechanisms within ...
BioTechniques

Innovative new tools map cell communication from spatial transcriptomics data

New simulator and computational tools generate realistic ‘virtual tissues’ and map cell-to-cell ‘conversations’ from spatial transcriptomics data, potentially accelerating AI-driven discoveries in ...
GEN

Spatial Biology Moves Cancer Research Forward

Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers critical insight ...
eLife

Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling

Computational assessment identifies probe binding errors in a widely used commercial platform for spatial transcriptomics.
ascopubs.org

Spatial transcriptomics analysis to predict response to immune checkpoint blockade (ICB) in recurrent or metastatic head and neck squamous cell cancer (RM-HNSCC).

Neoadjuvant immunotherapy in combination with chemotherapy in resectable locally advanced head and neck squamous cell carcinoma: A randomized, open label, phase II clinical trial. This is an ASCO ...
ascopubs.org

Spatial transcriptomics and functional mapping of the suppressive TME in primary breast tumor and breast-to-liver metastases.

Race-specific survival prediction models for de novo metastatic breast cancer using machine learning. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not ...