Paper in Cloning and Stem Cells shows that animal eggs do not support specific reprogramming toward the normal human embryonic state. Investigators at Advanced Cell Technology (ACTC) have found that ...

For decades, the idea of resetting the biological clock sounded more like speculative fiction than clinical strategy. The discovery of Yamanaka factors by Nobel laureate Shinya Yamanaka, which can ...

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies. Therefore, these methodologies often fail when applied ...

Scientists have produced stem cells from the endangered Grévy's zebra using human reprogramming factors. Further comprehensive gene analyses identified key genes that are also found in human and mouse ...

Researchers from Harvard Medical School, the University of Maine, and MIT have developed a method for reversing cellular aging. The groundbreaking research could be an alternative to gene therapy for ...

Zhou’s study, "TBX20 improves contractility and mitochondrial function during direct human cardiac reprogramming," was recently published in Circulation. The most common cause of death worldwide is ...

Mammalian hearts have almost no ability to grow new heart muscle cells, called cardiomyocytes, after birth. Thus, dead tissue after an adult heart attack is not repaired with new cardiomyocytes. It is ...